Not medical advice. This site does arithmetic and reports published information. It never tells you what dose to take. Talk to a licensed provider.
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Animal-onlyCosmetic use; not an approved drugCopper peptide GHKCu

GHK-Cu

A copper tripeptide widely used in topical skincare; injectable use is unproven.

Class
Copper-binding tripeptide
Sequence
Gly-His-Lys + Cu
Molar mass
~340 Da (GHK)
Half-life
Short
Human PK
Topical studied
Drug status
Not an approved drug
Cosmetic use
Common topically
Injectable dose
None established
Human evidenceAnimal-only
Read this first

There is no clinically validated human dose you can look up here, because for this compound one does not exist in the way regulated drugs have. We report what research and regulators actually say, and nothing more.

What it is

GHK-Cu is a naturally occurring copper-binding tripeptide (glycine-histidine-lysine plus copper) studied for skin remodeling, wound healing, and antioxidant effects. It is extremely common as a topical cosmetic ingredient.

The evidence, stated plainly

There is a reasonable body of laboratory and topical human research on skin and wound outcomes, which is why it appears in many cosmetics. Evidence for injected GHK-Cu doing what the topical does is far weaker, and it is not an approved injectable drug.

Why we grade this “Animal-only”

Evidence is largely preclinical (animal/in-vitro). We label evidence by its strongest honest tier, never by a vendor’s enthusiasm.

Half-life & timing

As a small peptide it clears quickly; most of the credible human data concerns topical application, not systemic injection.

Regulatory status

Used legally as a cosmetic ingredient topically. It is not an FDA-approved drug, and injectable use has no established dosing or approval.

Storage & handling

Topical formulations follow their product labels. Research powder for reconstitution follows standard peptide cold-storage handling.

The math is the dangerous part

Whatever dose a protocol or provider gave you, converting it to syringe units is where errors turn into 10× mistakes. Our calculator does only that conversion — it never invents the dose.

Open the reconstitution calculator

The honest bottom line

GHK-Cu is one of the better-supported peptides for topical skin use, which is a genuinely different claim from injecting it. Keep those two apart: the cosmetic evidence does not transfer to the needle.

Sources

  1. Topical/laboratory studies of GHK-Cu on skin and wound healing.
  2. Cosmetic-ingredient safety literature.
  3. General copper-peptide reviews.

Sourcing reflects literature available at publication and may change. See How We Rate Evidence.

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