What it is claimed to help
These are the uses attached to Mazdutide in research, clinical practice, or marketing. Listing a claim is not endorsing it — tap any of them to see every other compound carrying the same claim.
What the human evidence actually is
Randomised controlled human trials exist. Not necessarily approved, and not necessarily positive.
Multiple Chinese phase 3 trials (GLORY, DREAMS) reported meaningful weight and glycaemic benefit, leading to approval by China's NMPA in 2025. No FDA approval.
How it is supposed to work
Based on the natural hormone oxyntomodulin; agonises GLP-1 and glucagon receptors.
Safety
Class GI effects. Regulatory review outside China is incomplete.
Storage and handling
Lyophilised peptide is generally stored at 2–8 °C, or below −20 °C for long-term storage. Reconstituted in bacteriostatic water (0.9% benzyl alcohol) a solution is typically treated as usable for about 28 days refrigerated, versus roughly 24 hours for plain sterile water, which has no preservative. Add the water slowly down the vial wall and swirl — never shake, which shears peptide chains and foams the solution.
Whatever number a protocol or a prescriber gave you, converting it into syringe units is where a misplaced decimal becomes a tenfold error. Our calculators do that conversion and nothing else — they never invent a dose.
Open the calculatorsSources
- GLORY-1 phase 3, 2024
- China NMPA approval notice, 2025
Verified against primary sources on 27 August 2026. Regulatory status in this field changes several times a year. See How We Rate Evidence.